n Cardiovascular Journal of South Africa - Cross-over study of β-blockers shows further improvements : drug trends in cardiology

Volume 13, Issue 2
  • ISSN : 1680-0745



A cross-over comparison of carvedilol and metoprolol in patients with chronic heart failure was undertaken. This was to investigate any change of ventricular function, ventricular volumes and other haemodynamic parameters in patients who had responded well to either carvedilol or metoprolol treatment and were then switched to the alternative β-blocker.

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