n Cardiovascular Journal of South Africa - The jury is still out on oestrogens and oestrogen / progestin and the heart : letter to the editor

Volume 14, Issue 1
  • ISSN : 1680-0745



Extracted from text ... 'A case where hormone replacement therapy (HRT) was to be used for the sole purpose of primary prevention does not exist but in the minds of those inexperienced in clinical practise'1 clears misconceptions regarding indications for cardiovascular disease. Before discussing heart disease, 'primary prevention' requires definition. Vascular biologists suggest that it is the prevention of the progression of fatty streaks to atherosclerotic plaques, and cardiologists maintain it is the prevention of complicated plaques to avoid progresion to coronary heart disease events.2 Notelowitz3 suggests that the cardiologist's definition should be termed a 'primary intervention'. The Women's Health Initiative (WHI) Study, 4 by ..

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