n Cardiovascular Journal of South Africa - Policosanol - effective in lowering cholesterol in type 2 diabetes : drug trends in cardiology

Volume 14, Issue 2
  • ISSN : 1680-0745



Extracted from text ... Policosanol, a mixture of aliphatic pri-mary alcohols that are obtained from purified sugar cane wax, has been shown to be effective as a natural cho-lesterol- lowering agent in a double-blind placebo study in patients with type 2 diabetes. In this double-blind study 1 using 10 mg policosanol per day in patients with controlled non-insulin-dependent dia-betes mellitus (NIDDM), total choles-terol was reduced by 17%, LDL-C by 21.7% and a non-significant increase (6.5%) of HDL-C was achieved. Triglyceride concentrations, glucose levels and HbA1 values remained unchanged. An earlier pilot study, achieved even better results with an LDL-C decrease of 44% and an ..

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