n Cardiovascular Journal of South Africa - ACTION results of nifedipine in stable angina due next year : drug trends in cardiology

Volume 14, Issue 5
  • ISSN : 1680-0745



Extracted from text ... 283 ACTION is the first randomised, controlled, clinical trial to assess the effects of an anti-anginal drug - nifedipine gastrointestinal therapeutic system (nifedipine GITS) - on cardiovascular event-free survival in chronic, stable angina. The trial is ongoing; 7 700 patients have been entered into the study and results will be published in 2004, after 40 000 patient-years of follow-up. It is clearly a pivotal study in cardiovascular disease (CVD) risk management, because it will have a major impact on future therapy. Prof Poole-Wilson, chief investigator and head of the Department of Cardiac Medicine at the Imperial College in London, noted that ..

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