n Cardiovascular Journal of South Africa - Effectiveness of single detachable COOK(R) coils in closure of the patent ductus arteriosus : cardiovascular topics

Volume 15, Issue 2
  • ISSN : 1680-0745



&lt;I&gt;Objective:&lt;/I&gt; To assess the efficacy and safety of single detachable coils in the closure of PDAs. &lt;br&gt;&lt;I&gt;Methods:&lt;/I&gt; Review of cases in which a single detachable coil was implanted. The diameter of the ampulla was used to select coil size. Diameters of the PDA, ampulla and residual shunts were measured. &lt;br&gt;&lt;I&gt;Results:&lt;/I&gt; There were 36 patients with a mean minimal ductal diameter of 2.2 &lt;u&gt;+&lt;/u&gt; 0.6 mm. Immediately after implantation, 46% of the patients had residual shunts and after 24 hours, only 28%. A final spontaneous closure rate of 94% was observed after 21 months. There was a significant (p < 0.01) difference when minimal PDA diameter of those who had complete closure within 24 hours (median: 2 mm, interquartile range: 1.7-2.3 mm) was compared to those with a residual shunt (median: 2.5 mm, interquartile range: 2.3-3.2 mm). Negligible complications were experienced. &lt;br&gt;&lt;I&gt;Conclusion:&lt;/I&gt; Single Cook detachable coils are effective for PDA closure with a low complication rate if properly selected. There is a high rate of spontaneous closure of trivial residual shunts. In patients with a minimal ductal diameter &lt;u&gt;&gt;&lt;/u&gt; 2 mm and a residual shunt, more coils may be considered.

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