n Cardiovascular Journal of South Africa - PEACE - an important yet neutral study of low-risk patients with CAD : drug trends in cardiology

Volume 16, Issue 1
  • ISSN : 1680-0745



Extracted from text ... The PEACE trial, which was designed to assess the value of ACE inhibition therapy in addition to intensive modern therapy in patients with CAD and normal left ventricular function, has not shown additional benefit from ACE inhibition therapy in this low-risk patient group. Trandolapril therapy was, however, associated with effective blood pressure lowering and a reduction in new-onset diabetes. Announcing the results of the PEACE (Prevention of Events with Angiotension Converting Enzyme inhibition) study at the recent American Heart meeting in New Orleans, the co-chairman, Prof M.A. Pfeffer of Harvard Medical School emphasised that while prior studies such as HOPE ..

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