n Cardiovascular Journal of South Africa - LIFE echocardiography study confirms cardiac benefit : drug trends in cardiology

Volume 16, Issue 2
  • ISSN : 1680-0745



Extracted from text ... This sub-study within the LIFE trial was undertaken to examine the relative effectiveness of losartan (Cozaar) versus atenolol for regression of hyper - tensive LVH using echocardiography.1 Approximately 10% of the LIFE study participants underwent echocardiograms at baseline and yearly thereafter for five years. This is the largest study to date of regression of hypertensive LVH in terms of the numbers of echocardiograms, which provided the LV mass data. All echocardiograms were readblinded by the Cornell Medical Centre. Recordings were made by a standardised protocol, under which =?10 consecutive beats of 2-D and M-mode recordings of LV internal diameter and wall ..

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