n Cardiovascular Journal of South Africa - NT-proBNP measurements in high-risk diabetic patients - a case series from Mamelodi (Gauteng) : cardiovascular topic

Volume 17, Issue 2
  • ISSN : 1680-0745



The prevalence of raised BNP values is unknown in South African urban black populations at risk for heart failure. This study determined the frequency of raised NT-proBNP and the correlates of NT-proBNP in a high-risk diabetic population. <br><I>Methods:</I> A cross-sectional convenience sample of diabetic patients at the Mamelodi Hospital diabetes clinic was examined. Data on clinical, biometric, biochemical and a sixminute walk test were collected. <br><I>Results:</I> Sixty patients (38 female) were examined. The frequency of elevated NT-proBNP was 22% (95% CI; 12-34%). Univariate analysis found systolic blood pressure (BP) (p = 0.007) and duration of diabetes (p = 0.005) to be predictive of an elevated NT-proBNP.

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