n Cardiovascular Journal of Africa - Is double-blinding possible while administering fluids in the intensive care unit? : letter to the editor

Volume 24, Issue 4
  • ISSN : 1995-1892
  • E-ISSN: 1680-0745



The publication by Alavi SM highlights a subject with an ongoing debate, namely the 'crystalloid-colloid and colloid-colloid use following cardiac surgery'. They designed a randomised, double-blind clinical trial and compared the effects of three different solutions; 0.9% Ringer's lactate, 4% gelatin and 6% hydroxyethyl starch (HES) solution. They concluded that the HES solution was better in terms of the volume-expanding effect; lower amounts were required compared to the other two solutions, and short-term renal functions were better.

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