n Cardiovascular Journal of Africa - Intra-uterine growth restriction as a risk factor for hypertension in children six to 10 years old : cardiovascular topic
|Article Title||Intra-uterine growth restriction as a risk factor for hypertension in children six to 10 years old : cardiovascular topic|
|© Publisher:||Clinics Cardive Publishing|
|Journal||Cardiovascular Journal of Africa|
|Affiliations||1 Medical University of Lodz, Poland, 2 Medical University of Lodz, Poland, 3 Medical University of Lodz, Poland, 4 Medical University of Lodz, Poland, 5 Lodz University of Technology, Poland and 6 Polish Mother's Memorial Hospital Institute, Poland|
|Publication Date||Mar 2014|
|Pages||73 - 77|
|Keyword(s)||Birth weight, Children, Hypertension, Intra-uterine growth restriction and Small for gestational age|
Introduction : Intra-uterine growth restriction (IUGR) is present in about 3-10% of live-born newborns and it is as high as 20-30% in developing countries. Since the 1990s, it has been known that abnormalities during foetal growth may result in cardiovascular disease, including hypertension in adulthood.
Methods : This study evaluated blood pressure parameters (using ambulatory blood pressure monitoring) in children aged six to 10 years old, born as small for gestational age (SGA), and compared them to their healthy peers born as appropriate for gestational age (AGA).
Results : In the SGA group, an abnormal blood pressure level (prehypertension or hypertension) was present significantly more often than in the AGA group (50 vs 16%, p < 0.01). This relationship also occurred in association with the type of IUGR (asymmetric p < 0.01, symmetric p < 0.05).
Conclusion : In SGA children, abnormal blood pressure values occurred more frequently than in AGA children.
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