n Cardiovascular Journal of Africa - From the Editor's Desk
|Article Title||From the Editor's Desk|
|© Publisher:||Clinics Cardive Publishing|
|Journal||Cardiovascular Journal of Africa|
|Publication Date||Mar 2015|
It is difficult for those of us who trained in medicine prior to the advent of the epidemic of HIV/AIDS to explain to junior colleagues just how the epidemic has affected every aspect of medical practice, and the degree of complexity it has added. The timely review by Pillay and colleagues (page 70) of HIV-associated large-vessel vasculopathy, which surveys both the current and emerging spectrum of the condition, as seen in vascular surgical practice, serves to clarify some of the uncertainties around this complex problem. It is difficult to comprehend that the diverse disease spectrum of aneurysms, occlusive disease, spontaneous arteriovenous fistulae and dissections have a unifying pathogenesis and it may well be that further advances in knowledge will lead to re-classification and changes in terminology. The authors, importantly, highlight areas of therapeutic uncertainty, which hopefully will change with advances in the understanding of pathophysiology and a more structured approach to interventions.
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