n Cardiovascular Journal of Africa - Associations between body fat distribution, insulin resistance and dyslipidaemia in black and white South African women : cardiovascular topics

Volume 27 Number 3
  • ISSN : 1995-1892
  • E-ISSN: 1680-0745



The aim was to examine differences in body fat distribution between premenopausal black and white South African (SA) women and explore the ethnic-specific associations with cardiometabolic risk.

Body composition, using dual-energy X-ray absorptiometry (DXA) and computerised tomography, insulin resistance (HOMA-IR) and lipid levels were assessed in 288 black and 197 white premenopausal SA women.
Compared to the white women, black women had less central and more peripheral (lower-body) fat, and lower serum lipid and glucose concentrations, but similar homeostasis models for insulin resistance (HOMA-IR) values. The associations between body fat distribution and HOMA-IR, triglyceride and high-density lipoprotein cholesterol concentrations were similar, while the associations with fasting glucose, total and low-density lipoprotein cholesterol levels differed between black and white women.
Ethnic differences in body fat distribution are associated, in part, with differences in cardiometabolic risk between black and white SA women.

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