oa Cardiovascular Journal of Africa - The effort test as diagnostic aid in progressive familial heart block type I
Progressive familial heart block (PFHB) is an autosomal dominant inherited disorder that is usually asymptomatic. Affected members of such families are diagoosed on any of the foUowing electrocardiographic features: sinus bradycardia (SB), right bundle-branch block (RBBB), left anterior or left posterior hemlblocks, second-degree atrioventricular (A V) blocks aod complete beart block with broad or narrow QRS complexes. The aim of this study was to evaluate the effort test as a diagnostic aid to identity PFHB family members at risk. Seventy-nine pFHB members were subjected to an effort test (38 witb abnormal electrocardiograms (ReGs) and 41 with normal ECGs at rest). The commonest finding was the Inability of a significant number of members with abnormal ECGs to reach their target heart rate (X"" P < 0,05). Other ECG changes were also commoner in this group (Xl, p <0,0(5).
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