oa Cardiovascular Journal of Africa - Persistent pulmonary hypertension of the newborn with acute respiratory failure

Volume 5, Issue 2
  • ISSN : 1995-1892
  • E-ISSN: 1680-0745



Persistent pulmonary hypertension of the newborn (PPHN) may complicate severe respiratory failure in the neonate. The diagnosis of PPHN was made in 21 of 338 babies admitted to an intensive care unit over a 2-year period, i.e. 10,5 cases per year. Eleven were low-birth-weight (LBW) infants of whom 5 were small for gestational age. In those weighing over 2 500 g 3 were post-term and 5 small for gestational age. All the term babies had a history of fetal distress and 6 of the LBW infants had factors predisposing to asphyxia.

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