oa Cardiovascular Journal of Africa - Halothane anaesthesia is associated with improved post-cardiopulmonary bypass global myocardial function
|Article Title||Halothane anaesthesia is associated with improved post-cardiopulmonary bypass global myocardial function|
|© Publisher:||Clinics Cardive Publishing|
|Journal||Cardiovascular Journal of Africa|
|Affiliations||1 Department of Anaesthesiology, University of Stellenbosch, Tygerberg, Cape Town.|
|Publication Date||Apr 1995|
|Pages||72 - 77|
|Keyword(s)||Global myocardial function, Halothane anaesthesia and Post-cardiopulmonary bypass|
This study compared the effect of halothane and opiate anaesthesia on myocardial necrosis and reperfusion injury after coronary artery bypass surgery in patients. Except for the halothane and opiates, a similar anaesthetic technique was used in the two groups (10 patients each), including pre-induction beta-adrenergic blockade. The demographic data of the groups were similar and results indicated that there was no difference in the incidence of post-cardiopulmonary bypass arrhythmias. The creatine kinase myocardial fraction (CK-MB) in both groups increased after induction of anaesthesia (from 2,6 ï¿½ 0,9 to 5,6 ï¿½ 1,5%, mean and SEM for the opiate group and 1,3 ï¿½ 0,2 to 7,8 ï¿½ 1,7% for halothane patients).
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