oa Cardiovascular Journal of Africa - Comparison of ejection fractions obtained from radionuclide first-pass and gated equilibrium bloodpool studies

Volume 6, Issue 4
  • ISSN : 1995-1892
  • E-ISSN: 1680-0745



It is possible to determine left ventricular ejection fractions (LVEFs) from data acquired during the first-pass (FPASS) of the myocardial perfusion agent technetium- 99m sestamibi. This study was undertaken to determine which of three possible methods of analysis of FPASS data gave results which agreed best with the LVEFs calculated from routine gated equilibrium bloodpool studies. In the first method a time-activity curve was used with subtraction of background from a region of interest (ROI) around the left ventricle. Different ROIs were examined. The second and third methods employed a representative cycle. In the second method an extra-cardiac ROI was used for background correction and in the third method a summed frame obtained from the lung phase.

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