oa Cardiovascular Journal of Africa - Cardiac troponin T - a sensitive and specific new marker of myocardial damage in acute transmural infarction



Troponin T measurement is a relatively new diagnostic test to evaluate myocardial damage. The test was performed on sera from 52 patients, 42 with proven myocardial infarction (WHO criteria) and 10 control patients without myocardial infarction. The serum troponin T levels did not correlate with the serum creatine kinase levels. A raised serum troponin T level had a sensitivity of 95% and a specificity of 100% in predicting myocardial damage in patients with myocardial infarction. It was also raised for a longer period than serum creatine kinase levels, making it a sensitive and specific diagnostic test in the patient who presents 72 hours after a myocardial infarction.


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