oa Cardiovascular Journal of Africa - Association of annular subvalvular left ventricular aneurysms in children with tuberculosis - a possible aetiological relationship



The annular subvalvular left ventricular aneurysm (ASLVA) is a rare entity that occurs mostly in young blacks, predominantly from poor socio-economic groups in sub-Saharan Africa (82% of reported cases) and south India, areas with a high incidence of tuberculosis. Eighteen reports in the literature descriptionbe 25 children. A further 9 children are reported here. Rheumatic fever, bacterial endocarditis and tuberculosis have all been considered as possible causes of ASLVA. The association of tuberculosis (according to International Union Against Tuberculosis and Lung Disease criteria for diagnosis of childhood tuberculosis) suggests a tuberculous origin of ASLVA. Rheumatic fever and infective endocarditis characteristics were confirmed less often.


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