oa Cardiovascular Journal of Africa - Two roles for caveolae in the cardiac myocyte
The presence of caveolae in many cell types including heart myocytes is well established. It is hypothetised that caveolae may play a role in the storing of excess Ca2+ and may be instrumental in Ca2+ transients during contraction and relaxation' in pathological conditions. Furthermore, the presence of substances in caveolae and in their membranes may imply a role in the importing and exporting of key molecules under physiological and pathological conditions. Secretory activity is also suggested by an electron micrograph of rat heart muscle.
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