oa South African Journal of Chemistry - Fragmentation patterns in the mass spectra of 2,3-dihydro -2 -phenyl-l,4-benzoxazepin-5(411)-ones
|Article Title||Fragmentation patterns in the mass spectra of 2,3-dihydro -2 -phenyl-l,4-benzoxazepin-5(411)-ones|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Affiliations||1 Department of Chemistry, Rhodes University|
|Publication Date||Jan 1991|
|Pages||30 - 31|
Fragmentation patterns in the mass spectra of 2,3-dihydro-2- phenyl-1,4 -benzoxazepin-5 (4 H) -ones have been elucidated using a combination of low- and high-resolution mass spectrometry, Benzoxazepinones have been shown to exhibit a variety of phannacological effects, which include analgesic, antiinflammatory, anti-depressant, and anti-histaminic activity,' In the course of research on heterocyclic systems with medicinal potential, we have prepared a range of 2,3-dihydro- 2-phenyl-l,4-benzoxazepin-5(4H)-one derivatives and we now report the results of mass fragmentation studies of these compounds.
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