oa South African Journal of Chemistry - Fragmentation patterns in the mass spectra of 2,3-dihydro -2 -phenyl-l,4-benzoxazepin-5(411)-ones

Volume 44, Issue 1
  • ISSN : 0379-4350



Fragmentation patterns in the mass spectra of 2,3-dihydro-2- phenyl-1,4 -benzoxazepin-5 (4 H) -ones have been elucidated using a combination of low- and high-resolution mass spectrometry, Benzoxazepinones have been shown to exhibit a variety of phannacological effects, which include analgesic, antiinflammatory, anti-depressant, and anti-histaminic activity,' In the course of research on heterocyclic systems with medicinal potential, we have prepared a range of 2,3-dihydro- 2-phenyl-l,4-benzoxazepin-5(4H)-one derivatives and we now report the results of mass fragmentation studies of these compounds.

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