oa South African Journal of Chemistry - Dirhodium(II) Carbenes: A Rich Source of Chiral Products
|Article Title||Dirhodium(II) Carbenes: A Rich Source of Chiral Products|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Author||G.H.P. Roos and C.E. Raab|
|Publication Date||Jan 2001|
|Pages||1 - 40|
|Keyword(s)||Asymmetric synthesis, Carbenes, Diazocarbonyl compounds, Reviews and Rhodium|
The last decade has witnessed enormous growth in the asymmetric synthetic applications of dirhodium(II) carbenes generated from diazo-precursors. Innovative construction of 'designer' catalysts has played an integral role in extending the breadth of the synthetic cascade of non-racemic products now available through a range of cyclopropanation, C-X insertion, aromatic cycloaddition-rearrangement, and ylide-based reaction types. This review, whilst mindful of importance of the catalytic system, focuses primarily on the latter feature of product diversity.
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