1887

oa South African Journal of Chemistry - Synthesis and antimicrobial activity of new Thiazole-2(3)-thiones containing 1, 1, 3-trisubstituted Cyclobutane

 

Abstract

The reaction of potassium salts of RNHCSSK with 2-chloro-1-(3-methyl-3-phenylcyclobutyl)ethan-1-one in ethanol at 78-80°C afforded new 1, 3-thiazole-2(3<i>H</i>)-thiones containing 1, 1, 3-trisubstituted cyclobutane rings at C-4. The antimicrobial activities of these compounds were also investigated against seven different microorganisms, and some of them were found to be active against several of the microorganisms at higher concentrations.

Loading

Article metrics loading...

/content/chem/56/1/EJC24276
2003-01-01
2016-12-03
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error