oa South African Journal of Chemistry - An expedient method for the synthesis of acylhydrazones under microwave irradiation in solvent-free medium



A simple, efficient and eco-friendly method for the synthesis of acylhydrazones from acylhydrazides and aldehydes under microwave (MW) irradiation was reported, no solvent and catalyst was used. The method is combined with a combinatorial approach and fourteen novel acylhydrazones were synthesized in excellent yields (89-96%) and short reaction times (less than 5 min).


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