oa South African Journal of Chemistry - The Synthesis of 5-, 6-, 7- and 8-Membered Oxygen-containing Benzo-fused Rings using Alkene Isomerization and Ring-closing Metathesis Reactions

Volume 60, Issue 1
  • ISSN : 0379-4350



A number of benzo-fused oxygen-containing heterocycles were synthesized from allyl-3-isopropoxy-4-methoxybenzaldehyde using metathesis or an alkene isomerization-metathesis sequence as key synthetic steps. Benzo-fused compounds thus formed included a 3, 6-dihydro-1-2-benzoxocine, 1, 3-dihydro-benzo[]oxepine, 1-isochromene, 2, 3-dihydro-benzo[]oxepine, benzofuran and 2-chromene skeleton, demonstrating the versatility of this methodology.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error