oa South African Journal of Chemistry - Synthesis and antimicrobial activity of new α-aminophosphonic acid esters : research article
|Article Title||Synthesis and antimicrobial activity of new α-aminophosphonic acid esters : research article|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Author||Sanapalli S. Reddy, A.U. Ravi Sankar, C. Naga Raju and V. Koteswara Rao|
|Publication Date||Jan 2008|
|Pages||97 - 101|
|Keyword(s)||Antimicrobial activity, Aryl aldehydes, Diethyl / dimethylphosphite and Phenyl glycine ethyl ester|
Synthesis of new α-aminophosphonic acid esters (3a-1) was accomplished by the reaction of equimolar quantities of phenyl ethyl glycine and various aryl aldehydes with diethyl / dimethylphosphite in dry toluene at reflux temperature. All the structures of the newly synthesized α-aminophosphonic acid esters (3a-1) were established by elemental analysis, and IR, 1H, 13C, 31P NMR and mass spectral data. The antimicrobial and antifungal activities of these compounds were evaluated and they exhibited significant activity.
Article metrics loading...