oa South African Journal of Chemistry - Synthesis and biological activity of some Triazolothiadiazoles : research article

Volume 62, Issue 1
  • ISSN : 0379-4350



The synthesis of a series of novel 3-pyridyl-6-aryl-s-triazolo[3,4-b]-[1,3,4]-thiadiazoles is described. Fourteen new compounds were synthesized and characterized by spectral and elemental analyses. Some compounds were screened for antibacterial activity against , , and . Compounds containing aryl substituents at position 6 and the 1,2,4-triazole moiety at position 1 or 2 showed reasonable antibacterial activity.

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