oa South African Journal of Chemistry - Euphorbias of South Africa : two new phorbol esters from : research article

Volume 63, Issue 1
  • ISSN : 0379-4350



Two known phorbol esters, 12-deoxyphorbol-13-isobutyrate-20-acetate (1) and 12-deoxyphorbol-13-(2-methylbutyrate)-20-acetate (), and two new phorbol esters, 12-deoxyphorbol-13-isobutyrate-16-angelate-20-acetate () and 12-deoxyphorbol-13-(2-methylbutyrate)-16-angelate-20-acetate (), were isolated from the endemic South African plant . Standard spectroscopic techniques were used to elucidate the structures of all four compounds. The interaction of with opioid receptors was explored in an attempt to explain the unexplained stupor occasionally observed in herbivores browsing on .

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