oa South African Journal of Chemistry - Synthesis, characterization and antimicrobial studies of some novel 1,3,4-thiadiazolium-2-thiolate derivatives : research article
|Article Title||Synthesis, characterization and antimicrobial studies of some novel 1,3,4-thiadiazolium-2-thiolate derivatives : research article|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Author||Shahrukh T. Asundaria, Shreyas A. Patel, Kalpesh M. Mehta and Keshav C. Patel|
|Publication Date||Jan 2010|
|Pages||141 - 144|
|Keyword(s)||IR spectroscopy, Mesoionic, NMR spectroscopy, S-triazine, Thiadiazol and Veer Narmad South Gujarat University|
In this study, ten new 5-substituted-3-[4,6-di(morpholine-4-yl)-1,3,5-triazine-2-yl]-1,3,5-thiadiazolium-2-thiolate 6(a-j) were prepared via a five step procedure from the starting material 1,3,5-triazine (1). Structures of all synthesized compounds were confirmed by spectral data and elemental analyses. Newly synthesized compounds were tested for their antibacterial and antifungal activities against some important bacterial and fungal species. Some of the compounds were found to be moderately active against the tested organisms.
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