oa South African Journal of Chemistry - Synthesis, characterization and antimicrobial studies of some novel 1,3,4-thiadiazolium-2-thiolate derivatives : research article



In this study, ten new 5-substituted-3-[4,6-di(morpholine-4-yl)-1,3,5-triazine-2-yl]-1,3,5-thiadiazolium-2-thiolate () were prepared a five step procedure from the starting material 1,3,5-triazine (). Structures of all synthesized compounds were confirmed by spectral data and elemental analyses. Newly synthesized compounds were tested for their antibacterial and antifungal activities against some important bacterial and fungal species. Some of the compounds were found to be moderately active against the tested organisms.


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