oa South African Journal of Chemistry - Cyclohexenones through addition of ethyl acetoacetate to 3-aryl-1-(thiophen-3-yl)prop-2-en-1-one derivatives : research article
|Article Title||Cyclohexenones through addition of ethyl acetoacetate to 3-aryl-1-(thiophen-3-yl)prop-2-en-1-one derivatives : research article|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Author||Yakup Budak, Esra Findik and Mustafa Ceylan|
|Publication Date||Jan 2010|
|Pages||1 - 5|
|Keyword(s)||Cyclocondensation, Cyclohexenones, Ethyl acetoacetate and Michael addition|
Chalcone derivatives 3a-i containing a thiophene ring were prepared by the condensation of 1-(thiophen-3-yl)ethanone with aromatic aldehydes in excellent yields. The Michael addition of ethyl acetoacetate 4 to chalcone derivatives 3a-i resulted in the formation of nine novel ethyl 6-aryl-4-(3-thienyl)cyclohex-3-en-2-one-1-carboxylate derivatives 6a-i.
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