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oa South African Journal of Chemistry - Rapid synthesis of 2-substituted-2,3-dihydro-4(1)-quinazolinonesusing boric acid or sodium dihydrogen phosphateunder solvent-free conditions : research article

Volume 65, Issue 1
  • ISSN : 0379-4350

 

Abstract

Two efficient and convenient methods have been described for synthesis of 2-substituted-2,3-dihydro-4(1)-quinazolinone derivatives by one-pot condensation of 2-anthranilamide with aldehydes or ketones in the presence of a catalytic amount of boric acid or sodium dihydrogen phosphate under solvent-free conditions. The attractive features of these processes are short reaction times, easy isolation of products, excellent yields and an environmental friendly procedure.

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/content/chem/65/1/EJC24576
2012-01-01
2017-01-18

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