oa South African Journal of Chemistry - Rapid synthesis of 2-substituted-2,3-dihydro-4(1)-quinazolinonesusing boric acid or sodium dihydrogen phosphateunder solvent-free conditions : research article

Volume 65, Issue 1
  • ISSN : 0379-4350



Two efficient and convenient methods have been described for synthesis of 2-substituted-2,3-dihydro-4(1)-quinazolinone derivatives by one-pot condensation of 2-anthranilamide with aldehydes or ketones in the presence of a catalytic amount of boric acid or sodium dihydrogen phosphate under solvent-free conditions. The attractive features of these processes are short reaction times, easy isolation of products, excellent yields and an environmental friendly procedure.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error