oa South African Journal of Chemistry - Synthesis of novel bibrachial lariat ethers (BiBLEs) containing [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines : research article
|Article Title||Synthesis of novel bibrachial lariat ethers (BiBLEs) containing [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines : research article|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Affiliations||1 Islamic Azad University, Iran|
|Publication Date||Jan 2013|
|Pages||77 - 79|
|Keyword(s)||1,3,4-thiadiazines, Aza-crown, Bibrachial, Lariat ethers and Macrocycle|
A practical and regioselective method for the synthesis of cis-diastereomers of bibrachial lariat ethers (BiBLEs) bearing ester and amide groups is reported. The novel bibrachial lariat ethers (BiBLEs) 3a-d with neutral side chains were prepared by reaction of the corresponding aza-crown macrocycles 1a-b with ethyl chloroacetate and chloroacetamide.
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