oa South African Journal of Chemistry - A facile and practical p-toluenesulfonic acid catalyzed route to dicoumarols containing an aroyl group : research article
|Article Title||A facile and practical p-toluenesulfonic acid catalyzed route to dicoumarols containing an aroyl group : research article|
|© Publisher:||South African Chemical Institute (SACI)|
|Journal||South African Journal of Chemistry|
|Affiliations||1 Research Institute of Petroleum Industry, Iran, 2 Research Institute of Petroleum Industry, Iran, 3 Yasouj University, Iran and 4 Yasouj University, Iran|
|Publication Date||Jan 2015|
|Pages||53 - 56|
|Keyword(s)||4-hydroxycoumarin, Aryl glyoxal, Dicoumarol and p-toluenesulfonic acid|
New and known dicoumarols may be efficiently synthesized employing p-toluenesulfonic acid (p-TSA) as a solid acid catalyst from the reaction of 4-hydroxycoumarin with aryl glyoxal in water. This method offers direct access to structurally diverse coumarin derivatives in moderate to good yields (up to 65%). A total of five new compounds were synthesized.
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