oa South African Journal of Chemistry - investigation of the antimicrobial activity of a series of lipophilic phenols and naphthols : research article



Five groups of phenols/naphthols (42 compounds in total) were synthesized and screened against Gram-positive and , Gram-negative and , and the fungus . Whereas compounds were found inactive against Gram-negative bacteria, potent activities against Gram-positive bacteria were observed. The activities correlate with the ability of molecules to form quinone methides, suggesting potential new modes of action.


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