oa CSIR Science Scope - Engineering bacterial cell surfaces for new biotechnology applications

Volume 2, Issue 1
  • ISSN :



A recent discovery of biology is that peptides of interest can be expressed as fusions to proteins and displayed on the outside of the bacterial cell wall, giving rise to an expression system with many biotechnological and medical applications. An example of this technology is called cell surface display, where the peptide or protein of interest is the passenger protein, which attaches itself to the bacterial cell wall using an anchoring motif as its carrier. In this way the protein of interest is exposed to the outside of the bacterial cell.

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