n South African Pharmaceutical and Cosmetic Review - Taking anti-ageing to the next step : skin care

Volume 38, Issue 7
  • ISSN : 0257-2028



Among the many biological effects of the ageing process, skin ageing is one of the most visible. Skin ageing is caused by internal biological factors mixed with external factors like environmental effects such as UV exposure or pollutants. The dermis is the thicker layer of the skin and fibroblasts are the main cell type in the dermis. They produce collagen, elastin, other matrix proteins, and enzymes such as collagenase in order to maintain the structure of the extra cellular matrix (ECM).

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