n South African Pharmaceutical and Cosmetic Review - Evolving ingredients for anti-ageing products : anti-ageing

Volume 39, Issue 1
  • ISSN : 0257-2028



Phytosphingosine SLC is a derivative of the naturally-occurring phytosphingosine covalently coupled with salicylic acid. An in vivo study of the ingredient showed that it improves the condition of the stratum corneum from within with a 58 per cent increased barrier function. It does this by increasing the dermal collagen and strengthening the dermal epidermal junction (DEJ). The study showed that it outperformed retinoic acid, a typical anti-ageing ingredient.

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