n South African Pharmaceutical and Cosmetic Review - Disintegration in a flash : pharmaceutical focus

Volume 43, Issue 1
  • ISSN : 0257-2028



The use of orally disintegrating tablets (ODTs) has increased in recent years, especially in over-the-counter medicine applications. Roquette, which is represented by Orkila in South Africa, offers a new generation of co-processed excipients for ODT applications. Pearlitol Flash is a compound of mannitol and starch, designed to disintegrate rapidly, providing a smooth, creamy texture without a super disintegrant addition. Roquette has conducted a study on the dilution potential of Pearlitol Flash, which was evaluated using acetaminophen, an active ingredient used in hundreds of over-the-counter medicines.

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