n South African Pharmaceutical and Cosmetic Review - Spot-on analysis for micropellet coating : process & manufacturing technology

Volume 43, Issue 7
  • ISSN : 0257-2028



MUPS are a dosage form consisting of coated API pellets mixed with microcrystalline cellulose and pressed into tablets. Their main characteristic is the controlled release of the active ingredient, which is achieved by applying a functional coating to the pellets. The medication is absorbed in the intestine once the tablets have dissolved in the stomach. Since the pellets pass through the digestive cavity rapidly, MUPS tablets do not have to be taken on an empty stomach. They can be halved without losing their therapeutic efficacy. Cutting the tablets in two does not damage the sustained-release coating of the micropellets. All of this helps to improve patient compliance.

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