oa Interim : Interdisciplinary Journal - Acute coronary syndromes : pathophysiology and management. Implications for the South African population
Acute coronary syndromes (ACS) are the consequence of the development of coronary artery disease, which is the leading cause of death worldwide. ACS manifests as unstable angina or myocardial infarction and treatment strategies (which had been developed largely in Europe and North America) include medical or interventional therapy (percutaneous coronary intervention or coronary artery bypass graft surgery (CABG). CABG surgery is one of the most expensive elective procedures in a hospital. Several risk factors are known to be associated with morbidity and mortality after CABG intervention. Appropriate, cost-effective intervention requires detailed knowledge of the preoperative risk factors, validated for the varied ethnic composition of South Africa. 
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