n International SportMed Journal - The effects of creatine supplementation on muscle function and body composition in older men and women : review article
|Article Title||The effects of creatine supplementation on muscle function and body composition in older men and women : review article|
|© Publisher:||International Federation of Sports Medicine|
|Journal||International SportMed Journal|
|Author||Eric S. Rawson, Michael P. Conti and David J. Wassmer|
|Publication Date||Jan 2004|
|Pages||262 - 276|
|Keyword(s)||Aging, Creatine monohydrate, Fatigue, Muscle and Phosphocreatine|
Aging results in decreased muscle mass (i.e. sarcopenia), decreased muscle strength, and decreased ability to perform daily tasks. Creatine supplementation has been shown to increase lean body mass and muscle strength, and reduce muscle fatigue in young individuals. The beneficial effects of creatine previously demonstrated in younger subjects would be substantial to elderly persons. <br><I>Objective:</I> This review examines the effects of creatine supplementation on muscle function and body composition in elderly individuals. <br><I>Data sources:</I> PubMed and SPORTDiscus databases were searched using the terms aging, creatine, creatine supplementation, creatine monohydrate, elderly and older adults, and phosphocreatine. Additionally, the references of papers identified through this search were examined for relevant studies. <br><I>Study selection:</I> Ten studies were identified that examined the effects of creatine supplementation in older adults (>50 years). <br><I>Data extraction:</I> Studies were critically evaluated and summarised in this narrative review, no meta-analytic procedures were performed. <br><I>Data synthesis:</I> Approximately half of the available studies demonstrate a beneficial effect of creatine on muscle function and body composition in older individuals, less than what has been reported in young subjects. <br><I>Conclusions:</I> Some, but not all studies of creatine supplementation in older individuals demonstrate a beneficial effect on muscle function and body composition. Future studies should better characterise the habitual physical activity of older research subjects, as this appears to be an important determinant of whether there will be an effect of the creatine supplement. Additionally, no studies have been conducted examining the effects of creatine supplementation on frail, institutionalized elderly subjects, a particularly vulnerable population for muscle dysfunction and sarcopenia.
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