n CME : Your SA Journal of CPD - Hyperthyroidism : what the generalist should know : review

Volume 21, Issue 11
  • ISSN : 0256-2170



Extracted from text ... Thyrotoxicosis is one of the more com-mon endocrine disorders and most cases result from hyperactivity of the thyroid gland (hyperthyroidism) (Table I). THYROTOXICOSIS Younger patients with thyrotoxicosis of any cause may present with palpitations, anxiety, easy fatigability, psychomotor activity, diarrhoea, excessive sweating, heat intolerance, preference for cold, amenorrhoea, and marked weight loss without appetite loss. However, there is a small group of hyper-thyroid patients who describe weight gain at presentation as a result of increased appetite exceeding the increase in basal metabolic rate induced by excess thyroid hormones. The clinical features of tachycardia, tremor, sweating and lid lag associated with thyrotoxicosis suggest catecholamine excess. Yet circulating levels of cate-cholamines are normal and the increased sympathetic activity is accounted for by an increased number ..

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