n CME : Your SA Journal of CPD - Antiviral therapy in herpesvirus infections : main topic

Volume 21, Issue 6
  • ISSN : 0256-2170



Antiviral therapy for primary HSV infection has no effect on the subsequent rate of recurrences. <br>Antiviral therapy is of minimal clinical benefit for recurrent HSV infection in immunocompetent persons. <br>Patients who suffer frequent recurrences of genital herpes (( 6 a year) should be considered for prophylactic antiviral therapy for 6 months. <br>Avoiding exposure to ultraviolet light substantially reduces the incidence of recurrent herpes labialis. <br>Chronic HSV ulceration is one of the more common AIDS-defining illnesses in southern Africa and is frequently misdiagnosed. <br>Antiviral therapy is of very limited benefit in otherwise healthy patients with chickenpox. <br>In life-threatening HSV or VZV infections intravenous aciclovir is mandatory. <br>Antiviral therapy must be commenced within 72 hours of onset in immunocompetent patients with shingles. <br>Antiviral therapy for CMV has virtually no place in the management of primary infection in immunocompetent patients.

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