n CME : Your SA Journal of CPD - Evidence-based treatments for the asymptomatic HIV-positive patient in general practice : main topic

Volume 21, Issue 9
  • ISSN : 0256-2170



The asymtomatic HIV-positive patient represents a significant percentage of patients seen in general practice today in South Africa. <br>It is important and beneficial to know a patient's HIV status in order to prevent HIV-related morbidity and mortality. <br>Anti-TB drugs given prophylactically to HIV-positive and tuberculin skin-positive patients reduce their risk of active TB by as much as 70% in the short term (2 - 3 years). <br>Trimethoprim/sulfamethoxazole (TMP-SMX) - co-trimoxazole - is more effective than pentamidine or placebo and can reduce the risk of PCP or toxoplasmosis in patients who are HIV-positive by as much as 60%. <br>Women taking weekly fluconazole have a 58% decrease in the incidence of candidiasis compared with a 44% decrease in those taking placebo.

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