n CME : Your SA Journal of CPD - The natriuretic peptides : an expanding role in clinical medicine : main topic

Volume 22, Issue 1
  • ISSN : 0256-2170



NT-proBNP can be readily measured and an elevated level can be used to diagnose, or at least select, those patients who need further investigation for heart failure. <br>A normal level of NT-proBNP will effectively 'rule out' heart failure, especially in those patients without overt clinical signs of heart failure. <br>The higher the levels of NT-proBNP in heart failure patients, patients with an acute coronary syndrome or patients with a pulmonary embolus, the worse the prognosis. <br>In this manner elevated levels of NT-proBNP can guide the practitioner to increase the intensity of therapy.

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