n CME : Your SA Journal of CPD - Modafinil, newer anti-epileptic drugs, lipid lowering, and hormone therapy-associated asthma : medifile

Volume 22, Issue 8
  • ISSN : 0256-2170



Extracted from text ... MODAFINIL Modafinil has recently been approved by the South African Medicines Control Council (SAMCC) for the treatment of excessive daytime sleepiness (EDS) in patients with narcolepsy. It is registered as Provigil. The drug has also been used off-label for fatigue and sleepiness experienced by patients with multiple sclerosis (MS) and Parkinson's disease. Registered indication for modafinil: treatment of narcolepsy Modafinil is a unique wake-promoting agent that is chemically distinct from traditional stimulants. The precise mechanism of action in narcolepsy is not known, but it is believed to work selectively to activate the cortex of the brain. The drug is ..

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