n CME : Your SA Journal of CPD - More about : antiphospholipid antibodies and syndromes : relevance for the GP

Volume 23, Issue 10
  • ISSN : 0256-2170



Extracted from text ... Steroids Intra-articular steroids are useful and effective if only 1 - 2 joints are involved. In polyarticular involvement where NSAIDs/colchicine is contraindicated, intramuscular or oral steroids are alternatives, e.g. prednisone 0.5 mg/kg daily, weaning over 7 - 10 days. It is important to use lowdose NSAIDs or colchicine to prevent rebound flare-up once steroids are discontinued. Intercritical period (between flares) After the initial flare-up the patient may remain asymptomatic for many years. Therefore there is no need for ULDs, but over time these asymptomatic periods become shorter. Chronic gout This is characterised by more than 2 acute attacks per ..

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