n CME : Your SA Journal of CPD - Update on pharmacotherapy for weight control and obesity : main topic
|Article Title||Update on pharmacotherapy for weight control and obesity : main topic|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||CME : Your SA Journal of CPD|
|Author||M-T. Van der Merwe|
|Publication Date||Nov 2005|
|Pages||552 - 557|
Recent paradigm shifts in the understanding of obesity have led to the inclusion of weight loss drugs for treatment. These include a recognition that obesity is a true disease with genetic determinants (not a 'character flaw'), that it is a major public health threat, and that weight regain occurs after discontinuation of weight loss medication. <br>Pharmacological treatment of obesity is based on three possible principles: reduced food intake via appetite-regulating mechanisms in the brain, reduced gut absorption of dietary fat, and increased energy expenditure. <br>There is increasing evidence that obesity is a chronic disease, and as such, long-term pharmacotherapy may be safe and appropriate for some individuals.
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