n CME : Your SA Journal of CPD - AIDS overview




Extracted from text ... HIV TREATMENT AND VIRAL RESISTANCE: A GLOBAL PERSPECTIVE Genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral (ARV) treatment is expanded to regions where diverse non-subtype B viruses predominate. The HIV-1 pandemic resulted from the cross-species transmission of a lentivirus, probably of chimpanzee origin, that began spreading among humans during the first half of the previous century. The progeny of this zoonotic infection - designated HIV-1 group M (main) viruses - make up most HIV-1 infections. During their spread among humans, group M viruses have developed high genetic diversity. Most can ..


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