n CME : Your SA Journal of CPD - Clinical and laboratory evaluation of adverse reactions to drugs : main article
|Article Title||Clinical and laboratory evaluation of adverse reactions to drugs : main article|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||CME : Your SA Journal of CPD|
|Publication Date||Sep 2005|
|Pages||454 - 459|
Adverse reactions to drugs are common, and almost any drug can cause an adverse reaction. <br>True drug allergies occur when there is an allergic/hypersensitivity reaction with an immune basis. There is usually antibody production and/or histamine release (or sulphidoleukotriene release). <br>Most adverse reactions to drugs cause minor skin rashes. <br>The drug that most commonly causes reactions is penicillin. Penicillin reactions may affect most organs or systems and may cause a range of pathologies. <br>In suspected anaphylaxis, serial tryptase measurements may confirm the diagnosis. <br>There is no laboratory test to confirm SJS. It is diagnosed clinically and the drugs should not be reintroduced.
Article metrics loading...