n CME : Your SA Journal of CPD - Management of symptomatic menopausal women with breast cancer, benign breast disease or a family history of breast cancer : main article

Volume 24, Issue 11
  • ISSN : 0256-2170



The number of breast cancer survivors is increasing due to the increased use of mammographic screening and adjuvant therapy. <BR>Adjuvant therapy for breast cancer increases the severity of menopausal symptoms and the incidence of amenorrhoea. <BR>Overall data on risk of HRT on breast cancer survivors are inconclusive. <BR>SSRIs, gabapentin or clonidine may be the best of the non-hormonal agents for treatment of vasomotor symptoms. <BR>Non-hormonal agents are often ineffective and one-third of women are prepared to use HRT. <BR>HRT is the most efficacious treatment and is an option in women with severe vasomotor symptoms refractory to non-hormonal agents. <BR>Benign breast disease is a risk factor for breast cancer depending on histology and family history. <BR>Women with a family history of breast cancer are at increased risk depending on the degree and number of relatives and require close surveillance. <BR>HRT is not thought to increase the risk further in women with a family history of breast cancer, and HRT is not contraindicated.

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